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C E M Griffiths Selected Research

Biological Therapy

11/2021The risk of malignancy in patients with secukinumab-treated psoriasis, psoriatic arthritis and ankylosing spondylitis: analysis of clinical trial and postmarketing surveillance data with up to five years of follow-up.
11/2021Alcohol misuse is associated with poor response to systemic therapies for psoriasis: findings from a prospective multicentre cohort study.
11/2021The promise and challenges of cell therapy for psoriasis.
10/2021Defining trajectories of response in patients with psoriasis treated with biologic therapies.
4/2021Twelve-week secukinumab treatment is consistently efficacious for moderate-to-severe psoriasis regardless of prior biologic and non-biologic systemic treatment: Post hoc analysis of six randomised trials.
7/2020Phenotypic switch to eczema in patients receiving biologics for plaque psoriasis: a systematic review.
4/2020Risk of major cardiovascular events in patients with psoriasis receiving biologic therapies: a prospective cohort study.
1/2020Drug survival of adalimumab, ustekinumab and secukinumab in patients with psoriasis: a prospective cohort study from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR).
1/2020Psoriasis treat to target: defining outcomes in psoriasis using data from a real-world, population-based cohort study (the British Association of Dermatologists Biologics and Immunomodulators Register, BADBIR).
12/2019A standardization approach to compare treatment safety and effectiveness outcomes between clinical trials and real-world populations in psoriasis.
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C E M Griffiths Research Topics

Disease

127Psoriasis (Pustulosis Palmaris et Plantaris)
02/2022 - 03/2002
18Necrosis
12/2021 - 01/2002
11Psoriatic Arthritis
12/2021 - 03/2005
8Infections
11/2021 - 06/2005
7Inflammation (Inflammations)
04/2020 - 01/2002
6Skin Diseases (Skin Disease)
04/2020 - 10/2002
5Neoplasms (Cancer)
11/2021 - 07/2009
5Atopic Dermatitis (Atopic Eczema)
07/2020 - 08/2002
4Rheumatoid Arthritis
04/2015 - 05/2008
4Autoimmune Diseases (Autoimmune Disease)
04/2013 - 11/2002
3Myocardial Infarction
04/2020 - 04/2011
3Stroke (Strokes)
04/2020 - 04/2011
3Lichen Planus (Lichen Ruber Planus)
03/2012 - 07/2006
3Pyoderma Gangrenosum
07/2007 - 04/2006
2Chronic Disease (Chronic Diseases)
12/2021 - 12/2009
2Pruritus (Itching)
01/2018 - 12/2005
2Crohn Disease (Crohn's Disease)
04/2015 - 08/2007
2Wounds and Injuries (Trauma)
07/2014 - 03/2012
2Dermatitis
07/2007 - 07/2006
2Chronic Urticaria
07/2007 - 07/2006
2Blister (Bulla)
05/2006 - 05/2003
1Ankylosing Spondylitis
11/2021
1Obesity
11/2021
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
08/2021
1COVID-19
01/2021
1Eosinophilia
07/2020
1Eczema
07/2020
1Unstable Angina
04/2020
1Acute Coronary Syndrome
04/2020
1Anxiety Disorders (Anxiety Disorder)
01/2019
1Bipolar Disorder (Manic Depressive Psychosis)
01/2019

Drug/Important Bio-Agent (IBA)

21Biological ProductsIBA
12/2021 - 09/2005
19Etanercept (Enbrel)FDA Link
12/2021 - 10/2002
15Ustekinumab (CNTO 1275)FDA Link
12/2021 - 10/2010
14Adalimumab (Humira)FDA Link
01/2022 - 08/2009
13InterleukinsIBA
12/2021 - 07/2011
10CytokinesIBA
02/2016 - 01/2002
9Infliximab (Remicade)FDA Link
01/2019 - 10/2002
8Methotrexate (Mexate)FDA LinkGeneric
04/2020 - 11/2005
7secukinumabIBA
12/2021 - 04/2017
7Pharmaceutical PreparationsIBA
11/2021 - 04/2002
6Cyclosporine (Ciclosporin)FDA LinkGeneric
01/2019 - 04/2002
6Monoclonal AntibodiesIBA
01/2018 - 05/2002
6Proteins (Proteins, Gene)FDA Link
04/2016 - 10/2002
5Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2006 - 01/2002
4Immunoglobulin A (IgA)IBA
12/2021 - 01/2018
4guselkumabIBA
12/2021 - 01/2018
4Immunologic Factors (Immunomodulators)IBA
10/2021 - 12/2019
4Prostaglandins AIBA
01/2020 - 01/2015
3Interleukin-17 (Interleukin 17)IBA
12/2021 - 01/2018
3Interleukin-12 (IL 12)IBA
12/2021 - 04/2017
3Immunomodulating AgentsIBA
11/2021 - 04/2015
3ixekizumabIBA
01/2021 - 04/2017
3GoldIBA
01/2021 - 03/2011
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
04/2020 - 01/2012
3AcitretinFDA Link
01/2019 - 02/2006
2apremilastIBA
12/2021 - 01/2021
2Interleukin-23 Subunit p19IBA
11/2021 - 01/2021
2FumaratesIBA
01/2019 - 09/2005
2Biosimilar PharmaceuticalsIBA
03/2018 - 04/2017
2GP2015IBA
03/2018 - 04/2017
2tofacitinibIBA
02/2017 - 01/2015
2Janus Kinase InhibitorsIBA
02/2017 - 01/2015
2Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
06/2016 - 01/2012
2Sorafenib (BAY 43-9006)FDA Link
06/2016 - 01/2012
2IGF-I-IGFBP-3 complexFDA Link
04/2016 - 03/2011
2HLA-C Antigens (HLA-C)IBA
04/2015 - 01/2005
26-chloro-2-(1-piperazinyl)pyrazine (CPP)IBA
08/2014 - 02/2006
2omega-Chloroacetophenone (Mace)IBA
04/2013 - 04/2011
2AntigensIBA
03/2012 - 11/2002
2Interleukin-2 (IL2)IBA
03/2011 - 07/2003
2Alefacept (Amevive)FDA Link
08/2009 - 01/2005
2DNA (Deoxyribonucleic Acid)IBA
02/2009 - 02/2006
2Interferon-gamma (Interferon, gamma)IBA
08/2007 - 07/2003
2Interleukin-1beta (Interleukin 1 beta)IBA
08/2007 - 10/2005
2LactoferrinIBA
05/2003 - 01/2002
2Ointments (Pastes)IBA
01/2003 - 03/2002
1Indicators and Reagents (Reagents)IBA
02/2022
1Phosphodiesterase 4 InhibitorsIBA
01/2021
1Immunoglobulin E (IgE)IBA
07/2020
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
04/2020
1Complement System Proteins (Complement)IBA
04/2020
1Prostaglandins FIBA
04/2020
1Placenta Growth FactorIBA
04/2020
1Immunoglobulin G (IgG)IBA
01/2020
1risankizumabIBA
01/2019
1Psychotropic Drugs (Psychoactive Drugs)IBA
01/2019

Therapy/Procedure

51Therapeutics
12/2021 - 03/2002
28Biological Therapy
11/2021 - 08/2008
4Retreatment
02/2017 - 12/2009
4Phototherapy (Light Therapy)
09/2006 - 01/2005
3Photochemotherapy (Photodynamic Therapy)
07/2014 - 12/2004
3Lasers (Laser)
07/2009 - 01/2005
2Aftercare (After-Treatment)
08/2021 - 06/2016
2Duration of Therapy
01/2019 - 05/2004
2Drug Tapering
05/2017 - 06/2005
2Gas Lasers
01/2005 - 12/2002
1Cell- and Tissue-Based Therapy (Cell Therapy)
11/2021
1Treatment Delay
11/2021
1Immunomodulation
10/2018